Inhibits the activity of tyrosinase. By disrupting tyrosinase function, cysteamine reduces the production of melanin precursors, ultimately leading to a decrease in melanin synthesis. This mechanism results in the lightening of hyperpigmented areas.

Inhibits the activity of tyrosinase. By disrupting tyrosinase function, cysteamine reduces the production of melanin precursors, ultimately leading to a decrease in melanin synthesis. This mechanism results in the lightening of hyperpigmented areas.

Clinical studies have demonstrated the effectiveness of cysteamine in treating hyperpigmentation, including melasma and post-inflammatory hyperpigmentation, to be 1.5x stronger than hydroquinone. In a randomized controlled trial, patients with melasma who applied a topical cysteamine cream twice daily for two months experienced a significant reduction in pigmentation compared to the control group.

Peptides play a multifaceted role in lightening hyperpigmentation in the skin. These short chains of amino acids can influence various cellular processes related to melanin production and skin pigmentation. Oligopeptide-34 and -51, target hyperpigmentation by inhibiting tyrosinase.